2-NBDG (Highly Pure)

Product Description 4.8/5 - (24 votes) 2-NBDG Catalog number: MDP0879 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 0.5 mg Molecular Weight or Concentration: 342.26 g/mol Supplied as: Powder Applications: fluorescent tracer for monitoring glucose uptake in living cells Storage: -20°C Keywords: 2-[N-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-yl)Amino]-2- Deoxy-D-Glucose Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. Indication for Use:This product is for Research Use Only. This product is NOT for human or animal use. References: 1: Zou C, Wang Y, Shen Z. 2-NBDG as a fluorescent indicator for direct glucose uptake measurement. J Biochem Biophys Methods. 2005 Sep 30;64(3):207-15. 2: Chen Y, Zhang J, Zhang XY. 2-NBDG as a marker for detecting glucose uptake in reactive astrocytes exposed to oxygen-glucose deprivation in vitro. J Mol Neurosci. 2015 Jan;55(1):126-130. 3: Ogawa T, Sasaki A, Ono K, Ohshika S, Ishibashi Y, Yamada K. Uptake of fluorescent D- and L-glucose analogues, 2-NBDG and 2-NBDLG, into human osteosarcoma U2OS cells in a phloretin-inhibitable manner. Hum Cell. 2021 Mar;34(2):634-643. 4: Cai H, Peng F. 2-NBDG fluorescence imaging of hypermetabolic circulating tumor cells in mouse xenograft model of breast cancer. J Fluoresc. 2013 Jan;23(1):213-20. 5: Tao J, McCourt C, Sultana H, Nelson C, Driver J, Hackmann TJ. Use of a Fluorescent Analog of Glucose (2-NBDG) To Identify Uncultured Rumen Bacteria That Take Up Glucose. Appl Environ Microbiol. 2019 Mar 22;85(7):e03018-18. 6: Raeisi E, Mir LM. 2-NBDG, a fluorescent analogue of glucose, as a marker for detecting cell electropermeabilization in vitro. J Membr Biol. 2012 Oct;245(10):633-42. 7: Yamamoto T, Tanaka S, Suga S, Watanabe S, Nagatomo K, Sasaki A, Nishiuchi Y, Teshima T, Yamada K. Syntheses of 2-NBDG analogues for monitoring stereoselective uptake of D-glucose. Bioorg Med Chem Lett. 2011 Jul 1;21(13):4088-96. 8: Jin J, Qiu S, Wang P, Liang X, Huang F, Wu H, Zhang B, Zhang W, Tian X, Xu R, Shi H, Wu X. Cardamonin inhibits breast cancer growth by repressing HIF-1α-dependent metabolic reprogramming. J Exp Clin Cancer Res. 2019 Aug 27;38(1):377. 9: Yamada K, Saito M, Matsuoka H, Inagaki N. A real-time method of imaging glucose uptake in single, living mammalian cells. Nat Protoc. 2007;2(3):753-62. 10: Millon SR, Ostrander JH, Brown JQ, Raheja A, Seewaldt VL, Ramanujam N. Uptake of 2-NBDG as a method to monitor therapy response in breast cancer cell lines. Breast Cancer Res Treat. 2011 Feb;126(1):55-62. Products Related to 2-NBDG: Carbohydrates