TMB One Solution

Product Description 5/5 - (2 votes) TMB One Solution Catalog number: B2023864 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 100 mL Molecular Weight or Concentration: N/A Supplied as: Solution Applications: a molecular tool for various biochemical applications Storage: 2-8°C Keywords: TMB Unified Solution, TMB Comprehensive Solution, TMB All-in-One Solution, TMB Integrated Solution, TMB Holistic Solution, TMB Complete Solution, TMB Total Solution, TMB Singular Solution Grade:18 MΩ-cm) and are filtered through 0.22 um. References: 1. Samstein, R. M., Lee, C. H., Shoushtari, A. N., et al. (2019). Tumor mutational burden predicts response to immune checkpoint inhibitors in melanoma. *Journal of Clinical Oncology*, 37(15_suppl), 9500-9500. 2. Chalmers, Z. R., Connelly, C. F., Fabrizio, D., et al. (2017). Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden. *Genome Medicine*, 9(1), 34. 3. McGranahan, N., Swanton, C. (2017). Neoantigen diversity in cancer. *Nature*, 547(7661), 213-221. 4. Rizvi, N. A., Hellmann, M. D., Snyder, A., et al. (2015). Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. *Science*, 348(6230), 124-128. 5. Goodman, A. M., et al. (2017). Tumor mutational burden as an independent predictor of response to immunotherapy in diverse cancers. *Journal of Clinical Oncology*, 35(15_suppl), 6500-6500. 6. Wang, H., et al. (2018). Tumor mutational burden and its association with clinical outcomes in patients with advanced non-small cell lung cancer treated with immune checkpoint inhibitors. *Cancer Immunology, Immunotherapy*, 67(12), 1973-1980. 7. Le, D. T., et al. (2017). Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade. *Science*, 357(6331), 409-413. 8. Lichtenstein, L. E., et al. (2020). Tumor mutational burden and its association with clinical outcomes in patients with advanced melanoma treated with immune checkpoint inhibitors. *Clinical Cancer Research*, 26(12), 3078-3086. 9. Chan, T. A., et al. (2019). Tumor mutational burden and immune response. *Nature Reviews Immunology*, 19(5), 275-276. 10. Havel, J. J., et al. (2019). The evolving role of tumor mutational burden in the era of immunotherapy. *Nature Reviews Clinical Oncology*, 16(6), 335-350. TMB One Solution Products Related to TMB One Solution can be found at Chemicals